Difference between Nuclear reaction and Chemical reactions are as follows:
| NUCLEAR REACTION | CHEMICAL REACTION |
| Nuclear reaction takes place in the atom’s nucleus. | Electrons in the atom are responsible for chemical reactions. |
| Nuclear Structure of atomic species changes. | Nuclear Structure of atomic species remains unchanged. |
| Protons and neutrons react inside the nucleus. | Electrons react outside the nucleus. |
| It has a very high-energy change. | It involves only low energy change. |